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SKC800 AUTOMATIC STAINLESS STEEL BIOREACTOR

SKC800 pilot and production stainless steel bioreactor provides a new solution for the development of bioprocess with its excellent performance and moderate scale.

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SKC800 75L pilot and production stainless steel bioreactor provides new solutions for the development of bioprocesses

with its excellent performance and moderate scale.

It adopts the biological reaction process control algorithm independently developed by CEKG and has a highly

controllable culture environment. Through stirring, temperature, pH, DO, deep ventilation, surface ventilation, peristaltic

pump, defoaming and liquid level, weighing, The control of cold spot detection and additional analog input and output

provide suitable cell growth conditions to achieve batch culture, fed-batch culture and continuous perfusion culture,

thereby achieving high-density culture and high-yield production.

For fabric carrier adherent culture, especially for secreted products, e.g. CHO for EPO/TPO,

VERO cells for human rabies vaccine/Japanese encephalitis vaccine/COVID-19 vaccines/

MDCK cells for flu vaccines, etc.

For micro-carrier adherent culture, e.g. VERO cells/diploid cells for human rabies vaccine, etc

For suspension cell culture, e.g. CHO cell antibody/SF9 cell cervical cancer vaccine, etc.

Vessel volume
Total volume	40L 75L 150L 300L
Working volume	10.75-32.0L 18.75-60.0L 37.5-120.0L 75.5-240.0L
Control system	Siemens PLC, Siemens touch screen, 3 pumps, Ethernet interface, USB interface
Temperature control Agitating system	Water jacket, electrical-heater PID automatic control, Pt100 sensor, control accuracy ±0.1℃, PID control, temperature control range 8-45℃ above, Max. 60℃

Agitating form	Upper mixing, double seal（Bottom magnetic stirring optional）
Impeller	Pitched blade/basket impeller/cell lift impeller/spin filter impeller optional
Agitating speed Load	25-200rpm 25-150rpm 25-120rpm 25-100rpm

Weighing module	0-40kg Cascaded by pump	0-100kg Cascaded by pump	0-200kg Cascaded by pump	0-300kg Cascaded by pump
Sparger※	4 gas mixing, 1 or 4 thermal mass flow controllers optional
Overlay ※	4 gas mixing, 1 or 4 thermal mass flow controllers optional
Exhaust	Exhaust condenser, exhaust filter heater
Gas distributor※	Circinate. Micro and macro sparge optional
pH※	2-12, PID control cascaded by pumps/gas flow. ISM probe optional
DO※	0-200%, PID control, cascaded by agitation/pumps/gas flow. ISM probe/optical probe optional
Sterilization	Automatic SIP
Cold spot detection ※	Optional, cold spot monitoring and FO value calculation during sterilization in place
Pumps※	Fixed-speed pumps for addition/acid/base/anti-foam etc., speed 100PRM
Level and anti-foam※	1 level probe. High level probe optional
SCADA※	Optional. GMP/GAMP standards.
Utilities	Water: 50um filtration; industrial steam 30-35PSIG, pure steam 30-35PSIG; 4 gases 30-35PSIG

Power supply	AC380V，50/60Hz

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High quality solutions for the entire industry chain from materials to equipment

Wuhan CEKG TECH. Co., Ltd. owns its own brand CEKG, focusing on providing cell culture equipment and consumables for vaccine, cell and gene therapy, antibody, in vitro diagnosis and other industries. Through the unremitting efforts of the team, the company has become an advanced high-tech enterprise in the industry. It has applied for 46 patents, won the honorary title of high-tech enterprise, Wuhan City "Optical Valley Gazelle" enterprise and "Hubei Province Specialized, Special and new" enterprise, and passed the ISO9001 quality system certification.

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SKC800 AUTOMATIC STAINLESS STEEL BIOREACTOR

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